PERIPrem is an evidence-based bundle of care. The key papers used in developing the bundle are referenced below.

Shaffer, Michele L., Olivier Baud, Thierry Lacaze-Masmonteil, Outi M. Peltoniemi, Francesco Bonsante, and Kristi L. Watterberg. “Effect of prophylaxis for early adrenal insufficiency using low-dose hydrocortisone in very preterm infants: an individual patient data meta-analysis.” The Journal of paediatrics 207 (2019): 136-142.

Williams, Alessandra Glover, Sam Tuvey, Hayley McBain, Noshin Menzies, Sally Hedge, Sarah Bates, and Karen Luyt. “Perinatal excellence to reduce injury in preterm birth (PERIPrem) through quality improvement.” BMJ Open Quality 11, no. 3 (2022): e001904.

Helenius, Kjell, Nicholas Longford, Liisa Lehtonen, Neena Modi, and Chris Gale. “Association of early postnatal transfer and birth outside a tertiary hospital with mortality and severe brain injury in extremely preterm infants: observational cohort study with propensity score matching.” BMJ 367 (2019).

Travers, Colm P., and Waldemar A. Carlo. “Hospital transfer of extremely preterm infants.” BMJ 367 (2019).

Doyle, Lex W., Jeanie L. Cheong, Susanne Hay, Brett J. Manley, Henry L. Halliday, and Roger Soll. “Early (< 7 days) systemic postnatal corticosteroids for prevention of bronchopulmonary dysplasia in preterm infants.” Cochrane Database of Systematic Reviews 10 (2021).

Armstrong-Buisseret, Lindsay, Katie Powers, Jon Dorling, Lucy Bradshaw, Samantha Johnson, Eleanor Mitchell, and Lelia Duley. “Randomised trial of cord clamping at very preterm birth: outcomes at 2 years.” Archives of Disease in Childhood-Fetal and Neonatal Edition 105, no. 3 (2020): 292-298.

Full text available through your organisational library service:

Baud, Olivier, Clémence Trousson, Valérie Biran, Emilie Leroy, Damir Mohamed, Corinne Alberti, and PREMILOC Trial Group. “Association between early low-dose hydrocortisone therapy in extremely preterm neonates and neurodevelopmental outcomes at 2 years of age.” Jama 317, no. 13 (2017): 1329-1337.

Baud, Olivier, Laure Maury, Florence Lebail, Duksha Ramful, Fatima El Moussawi, Claire Nicaise, Véronique Zupan-Simunek et al. “Effect of early low-dose hydrocortisone on survival without bronchopulmonary dysplasia in extremely preterm infants (PREMILOC): a double-blind, placebo-controlled, multicentre, randomised trial.” The Lancet 387, no. 10030 (2016): 1827-1836.

Baud, Olivier, Clémence Trousson, Valérie Biran, Emilie Leroy, Damir Mohamed, and Corinne Alberti. “Two-year neurodevelopmental outcomes of extremely preterm infants treated with early hydrocortisone: treatment effect according to gestational age at birth.” Archives of Disease in Childhood-Fetal and Neonatal Edition 104, no. 1 (2019): F30-F35.

Yeo, Kee Thai, Reji Thomas, Sharon SW Chow, Srinivas Bolisetty, Ross Haslam, William Tarnow-Mordi, and Kei Lui. “Improving incidence trends of severe intraventricular haemorrhages in preterm infants< 32 weeks gestation: a cohort study.” Archives of Disease in Childhood-Fetal and Neonatal Edition 105, no. 2 (2020): 145-150.